ende

KINSHIP ANALYSIS

Informations

Nowadays very reliable kinship analyses can be performed by means of molecular genetic methods. For this purpose so called short tandem repeats (STRs) are used since a few years. These are short, non-coding repeated sequence elements spread over the whole genome. The pattern of the different STRs is unique for every person (except for monozygotic twins) and is referred to as the genetic fingerprint. Typical questions for example are paternity and sibling testing, and the analysis of same-gender twins concerning monozygosity and dizygosity respectively.

Paternity can be confirmed or excluded reliably and rapidly by molecular genetic analyses.

 For this purpose microsatellite analysis is performed. Microsatellites (MS) are DNA-stretches of variable length located in the non-coding parts of the genome. MS are randomly distributed over the whole genome and can be highly variable in length (polymorphic). Every human carries a twofold version (alleles) of every microsatellite. The individual pattern of MS – resulting out of the combination of the unique alleles – differs between every person, with the exception of monozygotic twins. Parents transmit one of their two alleles to their offspring which allows to confirmation or exclusion paternity by comparing the MS pattern between child and parents.

Since MS contain no information regarding hereditary characteristics (genes) no analysis of hereditary diseases or disease susceptibility genes is performed. Therefore, the protection of personality is retained.

In case you consider kinship analysis, please make an appointment for a genetic counselling inverview.
You may contact us by phone: +49 89/ 54 86 29 -0
Or send an Email to:
info@humane-genetik.de

Contact person

Diplombiologin Claudia Bayerl
Abteilung Molekulargenetik

 

089 / 54 86 29 - 0
089 / 54 86 29 -243
claudia.bayerl@synlab.com

 

Accreditation
A member of